Motif ID: FOX{F1,F2,J1}.p2

Z-value: 1.381


Transcription factors associated with FOX{F1,F2,J1}.p2:

Gene SymbolEntrez IDGene Name
FOXF1 2294 forkhead box F1
FOXF2 2295 forkhead box F2
FOXJ1 2302 forkhead box J1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
FOXJ1chr17_-_716489650.562.4e-02Click!
FOXF1chr16_+_85101734-0.401.3e-01Click!
FOXF2chr6_+_1335067-0.361.7e-01Click!


Activity profile for motif FOX{F1,F2,J1}.p2.

activity profile for motif FOX{F1,F2,J1}.p2


Sorted Z-values histogram for motif FOX{F1,F2,J1}.p2

Sorted Z-values for motif FOX{F1,F2,J1}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FOX{F1,F2,J1}.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_159459814 3.846 APOA2
apolipoprotein A-II
chr1_-_159459999 3.763 NM_001643
APOA2
apolipoprotein A-II
chr12_-_51629874 3.193 KRT8
keratin 8
chr17_+_69939130 3.121 NM_022036
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr14_-_20562962 2.884 NM_201538
NM_201539
NM_201540
NM_201541
NDRG2



NDRG family member 2



chr1_-_47468029 2.742 NM_003189
TAL1
T-cell acute lymphocytic leukemia 1
chr22_+_19458378 2.642 NM_000185
SERPIND1
serpin peptidase inhibitor, clade D (heparin cofactor), member 1
chr5_-_42847716 2.397 NM_001085486
NM_001093726
NM_005410
SEPP1


selenoprotein P, plasma, 1


chr17_-_7023283 2.384 ASGR1
asialoglycoprotein receptor 1
chr7_+_134483305 2.230 NM_018295
TMEM140
transmembrane protein 140
chr20_-_45410033 2.129 ZMYND8
zinc finger, MYND-type containing 8
chr13_+_49658016 2.086


chr11_-_117589283 1.932 NM_153206
AMICA1
adhesion molecule, interacts with CXADR antigen 1
chr2_-_233586145 1.848 NGEF
neuronal guanine nucleotide exchange factor
chr2_-_233586164 1.736 NM_019850
NGEF
neuronal guanine nucleotide exchange factor
chr12_+_119900931 1.727 NM_000545
HNF1A
HNF1 homeobox A
chr17_-_7023378 1.673 NM_001197216
NM_001671
ASGR1

asialoglycoprotein receptor 1

chr12_+_119900677 1.668 HNF1A
HNF1 homeobox A
chr12_-_101835026 1.665 PAH
phenylalanine hydroxylase
chr6_-_41823056 1.582 NM_001166424
NM_002630
PGC

progastricsin (pepsinogen C)

chr13_-_45654292 1.581 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr4_+_100714995 1.572 MTTP
microsomal triglyceride transfer protein
chr1_-_167822248 1.571 F5
coagulation factor V (proaccelerin, labile factor)
chr15_-_32398220 1.570 NM_005135
SLC12A6
solute carrier family 12 (potassium/chloride transporters), member 6
chr1_+_116455898 1.536 NM_152367
MAB21L3
mab-21-like 3 (C. elegans)
chr16_-_11282595 1.527 NM_002761
PRM1
protamine 1
chr13_-_45654327 1.477 NM_002298
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr14_+_104337923 1.467 NM_001137601
ZBTB42
zinc finger and BTB domain containing 42
chr13_-_45654296 1.464 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr19_-_53081326 1.445 SULT2A1
sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1
chr10_-_91395194 1.432 NM_148977
PANK1
pantothenate kinase 1
chr14_+_31868229 1.405 NM_004274
AKAP6
A kinase (PRKA) anchor protein 6
chr1_-_1346465 1.403 NM_001145210
LOC441869
hypothetical protein LOC441869
chr2_-_43919392 1.388 NM_022436
ABCG5
ATP-binding cassette, sub-family G (WHITE), member 5
chr6_-_138862271 1.384 NM_001144060
NHSL1
NHS-like 1
chr14_+_104338423 1.356 ZBTB42
zinc finger and BTB domain containing 42
chr10_-_69267774 1.351 NM_021800
NM_201262
DNAJC12

DnaJ (Hsp40) homolog, subfamily C, member 12

chr8_-_30121741 1.343 NM_001100916
MBOAT4
membrane bound O-acyltransferase domain containing 4
chr6_-_138862273 1.334


chr1_-_167822334 1.320 NM_000130
F5
coagulation factor V (proaccelerin, labile factor)
chr7_+_106292975 1.275 PIK3CG
phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr2_-_165133239 1.263 GRB14
growth factor receptor-bound protein 14
chr7_+_50318801 1.248 IKZF1
IKAROS family zinc finger 1 (Ikaros)
chr3_+_173043832 1.242 NM_001164436
TMEM212
transmembrane protein 212
chr10_-_52315390 1.203 A1CF
APOBEC1 complementation factor
chr22_-_35835548 1.198 TMPRSS6
transmembrane protease, serine 6
chr16_-_66590856 1.195 NM_022355
DPEP2
dipeptidase 2
chr6_+_32003180 1.190 NM_000063
NM_001145903
C2

complement component 2

chr1_+_40635058 1.173 NM_001198980
SMAP2
small ArfGAP2
chr2_+_143351695 1.165 KYNU
kynureninase
chr18_+_53863865 1.158 NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like
chr2_-_32344192 1.157 NM_021209
NLRC4
NLR family, CARD domain containing 4
chr2_+_169637255 1.154 NM_001142270
DHRS9
dehydrogenase/reductase (SDR family) member 9
chr19_+_17723285 1.137 NM_001161359
NM_015122
FCHO1

FCH domain only 1

chr12_-_61615124 1.135 PPM1H
protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr4_+_74488910 1.123 ALB
albumin
chr6_-_31740466 1.111 GPANK1
G patch domain and ankyrin repeats 1
chr10_-_5035967 1.078 NM_001135241
AKR1C1
AKR1C2
aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)
aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III)
chr4_+_74488835 1.077 NM_000477
ALB
albumin
chr8_-_110724594 1.076 NM_001099756
SYBU
syntabulin (syntaxin-interacting)
chr4_-_176971175 1.076 NM_201591
GPM6A
glycoprotein M6A
chr12_-_69837831 1.074 TSPAN8
tetraspanin 8
chr3_-_10522267 1.070 NM_001001331
NM_001683
ATP2B2

ATPase, Ca++ transporting, plasma membrane 2

chr20_-_22514092 1.064 NM_153675
FOXA2
forkhead box A2
chr6_+_64289585 1.063 PTP4A1
protein tyrosine phosphatase type IVA, member 1
chr1_-_57204208 1.045 NM_000066
C8B
complement component 8, beta polypeptide
chr17_+_64922420 1.038 NM_002758
MAP2K6
mitogen-activated protein kinase kinase 6
chr10_+_60606352 1.038 NM_032439
PHYHIPL
phytanoyl-CoA 2-hydroxylase interacting protein-like
chr9_-_85622366 1.037 NM_001135953
NM_025211
GKAP1

G kinase anchoring protein 1

chr7_+_106293112 1.028 NM_002649
PIK3CG
phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr5_+_154072654 1.021 NM_015315
LARP1
La ribonucleoprotein domain family, member 1
chr10_-_52315436 1.015 NM_001198818
NM_001198819
NM_001198820
NM_014576
NM_138932
NM_138933
A1CF





APOBEC1 complementation factor





chr7_-_140270749 1.010 NM_004333
BRAF
v-raf murine sarcoma viral oncogene homolog B1
chr6_-_26038817 0.984 NM_005835
SLC17A2
solute carrier family 17 (sodium phosphate), member 2
chr2_+_161980865 0.965 NM_006593
TBR1
T-box, brain, 1
chr7_+_111850367 0.962 NM_001007245
NM_001197080
IFRD1

interferon-related developmental regulator 1

chr2_+_201756048 0.944 CASP10
caspase 10, apoptosis-related cysteine peptidase
chr2_-_21084077 0.941 APOB
apolipoprotein B (including Ag(x) antigen)
chr1_-_205161821 0.926 NM_001193338
NM_001142473
NM_005449
FAIM3


Fas apoptotic inhibitory molecule 3


chr17_+_70244945 0.925 NM_001006638
NM_001163990
RAB37

RAB37, member RAS oncogene family

chrX_+_70232362 0.924 NM_001170931
NM_005938
FOXO4

forkhead box O4

chr2_+_143351536 0.922 NM_001032998
NM_003937
KYNU

kynureninase

chr4_+_39084867 0.919 NM_175737
KLB
klotho beta
chr3_-_10522340 0.900 ATP2B2
ATPase, Ca++ transporting, plasma membrane 2
chr6_+_154373323 0.896 NM_001145279
NM_001145280
NM_001145281
OPRM1


opioid receptor, mu 1


chr17_-_36418869 0.892 NM_031958
KRTAP3-1
keratin associated protein 3-1
chr10_+_4995597 0.890 AKR1C1
AKR1C3
aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)
aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr9_+_135276940 0.887 NM_139025
NM_139026
NM_139027
ADAMTS13


ADAM metallopeptidase with thrombospondin type 1 motif, 13


chr10_+_4995453 0.884 NM_001353
AKR1C1
aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)
chrX_-_153698930 0.884 HMGN1P37
high-mobility group nucleosome binding domain 1 pseudogene 37
chr10_-_50066386 0.883 NM_001010863
C10orf128
chromosome 10 open reading frame 128
chr6_+_32230172 0.883 PPT2
palmitoyl-protein thioesterase 2
chr7_-_25234582 0.876 NM_022150
NPVF
neuropeptide VF precursor
chr4_+_69716298 0.875 NM_001075
NM_001144767
UGT2B10

UDP glucuronosyltransferase 2 family, polypeptide B10

chr2_-_87156616 0.873 LOC285074
anaphase promoting complex subunit 1 pseudogene
chr17_-_23721485 0.869 NM_000638
VTN
vitronectin
chr6_+_32229599 0.868 NM_005155
PPT2-EGFL8
PPT2
PPT2-EGFL8 read-through transcript
palmitoyl-protein thioesterase 2
chr4_+_22608252 0.860


chr12_-_94914133 0.857 NM_002108
HAL
histidine ammonia-lyase
chr18_-_50777634 0.852 NM_025214
CCDC68
coiled-coil domain containing 68
chr1_+_196874867 0.852 PTPRC
protein tyrosine phosphatase, receptor type, C
chr17_-_23721468 0.841 VTN
vitronectin
chr22_+_29696662 0.841


chr2_-_135498716 0.831 NM_001018046
NM_025052
YSK4

YSK4 Sps1/Ste20-related kinase homolog (S. cerevisiae)

chr6_+_44352443 0.826 TMEM151B
transmembrane protein 151B
chr2_+_86800940 0.824 RMND5A
required for meiotic nuclear division 5 homolog A (S. cerevisiae)
chr13_-_48873735 0.818 NM_030925
CAB39L
calcium binding protein 39-like
chr10_+_102722275 0.817 NM_017893
SEMA4G
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
chr4_+_88939725 0.815 NM_004967
IBSP
integrin-binding sialoprotein
chr4_+_39084936 0.811 KLB
klotho beta
chr19_+_18357966 0.807 NM_004864
GDF15
growth differentiation factor 15
chr2_+_201755865 0.802 NM_001230
NM_032974
NM_032977
CASP10


caspase 10, apoptosis-related cysteine peptidase


chr2_+_176761552 0.801 NM_024501
HOXD1
homeobox D1
chr2_+_43919606 0.797 NM_022437
ABCG8
ATP-binding cassette, sub-family G (WHITE), member 8
chr4_-_123761615 0.795 NM_021803
IL21
interleukin 21
chr3_-_71376919 0.793 FOXP1
forkhead box P1
chr14_+_94148466 0.793 NM_001085
SERPINA3
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
chr12_-_69838045 0.792 NM_004616
TSPAN8
tetraspanin 8
chr5_-_169657360 0.791 LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr15_-_38387410 0.790 NM_004573
PLCB2
phospholipase C, beta 2
chr11_-_114880275 0.781 NM_001098517
NM_014333
CADM1

cell adhesion molecule 1

chr12_+_130004404 0.781 NM_198827
GPR133
G protein-coupled receptor 133
chr5_+_137701122 0.780 NM_001135647
FAM53C
family with sequence similarity 53, member C
chr8_+_82807218 0.779 NM_152284
CHMP4C
chromatin modifying protein 4C
chr10_+_4995685 0.773 AKR1C1
aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)
chr19_-_51979838 0.768 NM_001145145
SLC1A5
solute carrier family 1 (neutral amino acid transporter), member 5
chr6_+_30238961 0.768 NM_033229
TRIM15
tripartite motif containing 15
chr6_+_112481970 0.766 NM_003880
NM_198239
WISP3

WNT1 inducible signaling pathway protein 3

chr4_-_186969041 0.762 NM_001145672
SORBS2
sorbin and SH3 domain containing 2
chrX_-_48578878 0.762 NM_013271
PCSK1N
proprotein convertase subtilisin/kexin type 1 inhibitor
chr5_-_169657395 0.757 NM_005565
LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr20_-_42561725 0.756


chr19_+_15612706 0.750 NM_000896
CYP4F3
cytochrome P450, family 4, subfamily F, polypeptide 3
chr4_+_172971149 0.740 NM_001034845
GALNTL6
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 6
chr5_+_171553780 0.737 NM_001171183
EFCAB9
EF-hand calcium binding domain 9
chr5_-_169657312 0.737 LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr9_+_135277264 0.737 ADAMTS13
ADAM metallopeptidase with thrombospondin type 1 motif, 13
chr6_-_50025115 0.733 NM_001166478
DEFB133
defensin, beta 133
chr14_-_22358752 0.728 NM_001126106
SLC7A7
solute carrier family 7 (cationic amino acid transporter, y+ system), member 7
chr15_-_38387357 0.728 PLCB2
phospholipase C, beta 2
chr1_+_28134090 0.726 NM_001009568
NM_014474
SMPDL3B

sphingomyelin phosphodiesterase, acid-like 3B

chr9_-_115880494 0.723 NM_001633
AMBP
alpha-1-microglobulin/bikunin precursor
chr4_+_35962038 0.720 NM_001170700
DTHD1
death domain containing 1
chr17_-_43390108 0.719 NM_024320
PRR15L
proline rich 15-like
chr1_+_190811479 0.718 NM_002922
RGS1
regulator of G-protein signaling 1
chr2_-_180319013 0.716 NM_001113397
ZNF385B
zinc finger protein 385B
chr6_-_25834733 0.715 NM_170745
HIST1H2AA
histone cluster 1, H2aa
chr17_-_23721430 0.713 VTN
vitronectin
chr5_-_59819642 0.712 NM_001165899
PDE4D
phosphodiesterase 4D, cAMP-specific
chr5_-_169657192 0.709 LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr1_+_144149794 0.708 NM_006472
TXNIP
thioredoxin interacting protein
chr1_-_24067347 0.701 NM_000147
FUCA1
fucosidase, alpha-L- 1, tissue
chr16_+_11346780 0.697 NM_152308
C16orf75
chromosome 16 open reading frame 75
chr9_-_205892 0.696 NM_152569
C9orf66
chromosome 9 open reading frame 66
chr18_+_30327341 0.694 DTNA
dystrobrevin, alpha
chr4_+_187424336 0.690 F11
coagulation factor XI
chrX_+_57329834 0.687 NM_174912
FAAH2
fatty acid amide hydrolase 2
chr17_-_23721420 0.685 VTN
vitronectin
chr7_+_149733309 0.685


chr9_-_115880366 0.682 AMBP
alpha-1-microglobulin/bikunin precursor
chr7_+_77307382 0.667 NM_001127357
NM_001127359
NM_020432
PHTF2


putative homeodomain transcription factor 2


chr17_+_38178969 0.662 NM_032353
VPS25
vacuolar protein sorting 25 homolog (S. cerevisiae)
chr17_-_23721351 0.661 VTN
vitronectin
chr1_+_198278339 0.658 NR5A2
nuclear receptor subfamily 5, group A, member 2
chr2_-_39201631 0.654 SOS1
son of sevenless homolog 1 (Drosophila)
chr17_+_69950782 0.654 GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr15_-_38387164 0.653 PLCB2
phospholipase C, beta 2
chr11_+_22644732 0.645 NM_001143830
GAS2
growth arrest-specific 2
chr14_-_20636568 0.645 NM_016423
ZNF219
zinc finger protein 219
chr20_+_23293020 0.642 NM_022482
GZF1
GDNF-inducible zinc finger protein 1
chr9_-_115880281 0.638 AMBP
alpha-1-microglobulin/bikunin precursor
chr12_-_31370305 0.638 FAM60A
family with sequence similarity 60, member A
chr18_+_53170718 0.633 NM_015879
ST8SIA3
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
chr5_+_147754467 0.631 FBXO38
F-box protein 38
chr2_+_86800898 0.631 NM_022780
RMND5A
required for meiotic nuclear division 5 homolog A (S. cerevisiae)
chr2_+_86801081 0.628 RMND5A
required for meiotic nuclear division 5 homolog A (S. cerevisiae)
chr16_+_716936 0.616 NM_207112
NM_032304
HAGHL

hydroxyacylglutathione hydrolase-like

chr1_-_24342158 0.615 NM_021258
IL22RA1
interleukin 22 receptor, alpha 1
chr10_-_54201400 0.615 NM_000242
MBL2
mannose-binding lectin (protein C) 2, soluble
chr11_-_116213511 0.605 NM_000039
APOA1
apolipoprotein A-I
chr17_-_73636386 0.604 NM_001127198
TMC6
transmembrane channel-like 6
chr4_+_187424111 0.598 NM_000128
F11
coagulation factor XI
chr17_+_75366524 0.597 NM_005189
NM_032647
CBX2

chromobox homolog 2

chr1_-_31117948 0.593 SDC3
syndecan 3
chr6_+_32229771 0.590 PPT2-EGFL8
PPT2
PPT2-EGFL8 read-through transcript
palmitoyl-protein thioesterase 2
chr11_-_102331643 0.584 NM_002427
MMP13
matrix metallopeptidase 13 (collagenase 3)
chr5_-_110090264 0.583 NM_001039763
TMEM232
transmembrane protein 232
chr11_-_16953135 0.582 RPL36A
ribosomal protein L36a
chr11_-_63690069 0.577 NM_014067
MACROD1
MACRO domain containing 1
chr18_+_30327243 0.576 NM_001198945
NM_001392
NM_032975
NM_032979
DTNA



dystrobrevin, alpha



chr4_-_38710376 0.570 NM_024943
TMEM156
transmembrane protein 156
chr16_+_11346812 0.569 C16orf75
chromosome 16 open reading frame 75
chr1_+_74473672 0.566 NM_015978
TNNI3K
TNNI3 interacting kinase
chr14_-_99140195 0.566 NM_001144995
CCDC85C
coiled-coil domain containing 85C
chr7_+_106292932 0.560 PIK3CG
phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr17_-_72151314 0.559 NM_018414
ST6GALNAC1
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1
chr10_+_70517863 0.558 SRGN
serglycin
chr12_-_31370351 0.555 FAM60A
family with sequence similarity 60, member A
chr12_+_77963563 0.552 NM_001135806
SYT1
synaptotagmin I
chr10_+_70517823 0.552 NM_002727
SRGN
serglycin

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
4.81 2.08e-02 GO:0002455 humoral immune response mediated by circulating immunoglobulin
4.55 3.77e-02 GO:0008206 bile acid metabolic process
4.94 4.12e-02 GO:0006958 complement activation, classical pathway

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.26 6.24e-04 GO:0071944 cell periphery
1.26 6.30e-04 GO:0005886 plasma membrane
1.13 2.79e-02 GO:0016020 membrane

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.37 6.84e-03 GO:0004871 signal transducer activity
1.37 6.84e-03 GO:0060089 molecular transducer activity
1.48 9.18e-03 GO:0004888 transmembrane receptor activity
1.40 1.15e-02 GO:0004872 receptor activity
1.59 1.16e-02 GO:0004930 G-protein coupled receptor activity